![]() ![]() ![]() If the particle moves in the direction of increasing electric field, the behavior is referred to as positive DEP (sometime pDEP), if acting to move the particle away from high field regions, it is known as negative DEP (or nDEP). Since the direction of the force is dependent on field gradient rather than field direction, DEP will occur in AC as well as DC electric fields polarization (and hence the direction of the force) will depend on the relative polarizabilities of particle and medium. The orientation of the dipole is dependent on the relative polarizability of the particle and medium, in accordance with Maxwell–Wagner–Sillars polarization. Since the field is non-uniform, the pole experiencing the greatest electric field will dominate over the other, and the particle will move. The electric field polarizes the particle, and the poles then experience a force along the field lines, which can be either attractive or repulsive according to the orientation on the dipole. Recently, dielectrophoresis has been revived due to its potential in the manipulation of microparticles, nanoparticles and cells.ĭielectrophoresis occurs when a polarizable particle is suspended in a non-uniform electric field. 4.3 Dielectrophoresis field-flow fractionationĪlthough the phenomenon we now call dielectrophoresis was described in passing as far back as the early 20th century, it was only subject to serious study, named and first understood by Herbert Pohl in the 1950s. ![]() 3.1 DEP as a cell characterisation tool.
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